Publications
For a full list of publications, please visit Dr. Puig's Google Scholar page linked here.
Selected Publications:
Gamble MC, Williams BR, Singh N, Posa L, Freyberg Z, Logan RW, Puig S. Mu-opioid receptor and receptor tyrosine kinase crosstalk: Implications in mechanisms of opioid tolerance, reduced analgesia to neuropathic pain, dependence, and reward. Front Syst Neurosci. 2022 Dec 1;16:1059089. doi: 10.3389/fnsys.2022.1059089. PMID: 36532632; PMCID: PMC9751598. https://pubmed.ncbi.nlm.nih.gov/36532632/
Puig S, Gutstein HB. Opioids: keeping the good, eliminating the bad. Nat Med. 2017 Mar;23(3):272-273. doi: 10.1038/nm.4277. Epub 2017 Jan 30. PMID: 28134927; PMCID: PMC6602584. https://pubmed.ncbi.nlm.nih.gov/28134927/
Puig S, Barker KE, Szott SR, Kann PT, Morris JS, Gutstein HB. Spinal Opioid Tolerance Depends upon Platelet-Derived Growth Factor Receptor-β Signaling, Not μ-Opioid Receptor Internalization. Mol Pharmacol. 2020 Oct;98(4):487-496. doi: 10.1124/mol.120.119552. Epub 2020 Jul 28. PMID: 32723769; PMCID: PMC7562976. https://pubmed.ncbi.nlm.nih.gov/32723769/
Puig S, Donica CL, Gutstein HB. EGFR Signaling Causes Morphine Tolerance and Mechanical Sensitization in Rats. eNeuro. 2020 Apr 6;7(2):ENEURO.0460-18.2020. doi: 10.1523/ENEURO.0460-18.2020. PMID: 32111605; PMCID: PMC7218007. https://pubmed.ncbi.nlm.nih.gov/32111605/
Puig S, Shelton MA, Barko K, Seney ML, Logan RW. Sex-specific role of the circadian transcription factor NPAS2 in opioid tolerance, withdrawal and analgesia. Genes Brain Behav. 2022 Sep;21(7):e12829. doi: 10.1111/gbb.12829. Epub 2022 Aug 20. PMID: 36053258; PMCID: PMC9744556. https://pubmed.ncbi.nlm.nih.gov/36053258/
Puig S, Xue X, Salisbury R, Shelton MA, Kim SM, Hildebrand MA, Glausier JR, Freyberg Z, Tseng GC, Yocum AK, Lewis DA, Seney ML, MacDonald ML, Logan RW. Circadian rhythm disruptions associated with opioid use disorder in synaptic proteomes of human dorsolateral prefrontal cortex and nucleus accumbens. Mol Psychiatry. 2023 Sep 6. doi: 10.1038/s41380-023-02241-6. Epub ahead of print. PMID: 37674018. https://pubmed.ncbi.nlm.nih.gov/37674018/
Gayden J, Puig S, Srinivasan C, Buck SA, Gamble MC, Glausier JR, Tejeda HA, Dong Y, Pfenning AR, Logan RW, Freyberg Z. Three-dimensional characterization of medium spiny neuron heterogeneity in the adult mouse striatum. bioRxiv [Preprint]. 2023 May 5:2023.05.04.539488. doi: 10.1101/2023.05.04.539488. PMID: 37205475; PMCID: PMC10187292. https://pubmed.ncbi.nlm.nih.gov/37205475/