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Thompson Lab
Biochemistry and Molecular Biotechnology
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Our most recent publications:
Total:
displaying 10 out of
100
results
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
lunes, octubre 21, 2024
Author(s):
Luis M García-Marín,Adrian I Campos,Santiago Diaz-Torres,Jill A Rabinowitz,Zuriel Ceja,Brittany L Mitchell,Katrina L Grasby,Jackson G Thorp,Ingrid Agartz,Saud Alhusaini,David Ames,Philippe Amouyel,Ole A Andreassen,Konstantinos Arfanakis,Alejandro Arias-Vasquez,Nicola J Armstrong,Lavinia Athanasiu,Mark E Bastin,Alexa S Beiser,David A Bennett,Joshua C Bis,Marco P M Boks,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Jan K Buitelaar,Ralph Burkhardt,Wiepke Cahn,Vince D Calhoun,Owen T Carmichael,Mallar Chakravarty,Qiang Chen,Christopher R K Ching,Sven Cichon,Benedicto Crespo-Facorro,Fabrice Crivello,Anders M Dale,George Davey Smith,Eco J C de Geus,Philip L De Jager,Greig I de Zubicaray,Stéphanie Debette,Charles DeCarli,Chantal Depondt,Sylvane Desrivières,Srdjan Djurovic,Stefan Ehrlich,Susanne Erk,Thomas Espeseth,Guillén Fernández,Irina Filippi,Simon E Fisher,Debra A Fleischman,Evan Fletcher,Myriam Fornage,Andreas J Forstner,Clyde Francks,Barbara Franke,Tian Ge,Aaron L Goldman,Hans J Grabe,Robert C Green,Oliver Grimm,Nynke A Groenewold,Oliver Gruber,Vilmundur Gudnason,Asta K Håberg,Unn K Haukvik,Andreas Heinz,Derrek P Hibar,Saima Hilal,Jayandra J Himali,Beng-Choon Ho,David F Hoehn,Pieter J Hoekstra,Edith Hofer,Wolfgang Hoffmann,Avram J Holmes,Georg Homuth,Norbert Hosten,M Kamran Ikram,Jonathan C Ipser,Clifford R Jack,Neda Jahanshad,Erik G Jönsson,Rene S Kahn,Ryota Kanai,Marieke Klein,Maria J Knol,Lenore J Launer,Stephen M Lawrie,Stephanie Le Hellard,Phil H Lee,Hervé Lemaître,Shuo Li,David C M Liewald,Honghuang Lin,W T Longstreth,Oscar L Lopez,Michelle Luciano,Pauline Maillard,Andre F Marquand,Nicholas G Martin,Jean-Luc Martinot,Karen A Mather,Venkata S Mattay,Katie L McMahon,Patrizia Mecocci,Ingrid Melle,Andreas Meyer-Lindenberg,Nazanin Mirza-Schreiber,Yuri Milaneschi,Thomas H Mosley,Thomas W Mühleisen,Bertram Müller-Myhsok,Susana Muñoz Maniega,Matthias Nauck,Kwangsik Nho,Wiro J Niessen,Markus M Nöthen,Paul A Nyquist,Jaap Oosterlaan,Massimo Pandolfo,Tomas Paus,Zdenka Pausova,Brenda W J H Penninx,G Bruce Pike,Bruce M Psaty,Benno Pütz,Simone Reppermund,Marcella D Rietschel,Shannon L Risacher,Nina Romanczuk-Seiferth,Rafael Romero-Garcia,Gennady V Roshchupkin,Jerome I Rotter,Perminder S Sachdev,Philipp G Sämann,Arvin Saremi,Muralidharan Sargurupremraj,Andrew J Saykin,Lianne Schmaal,Helena Schmidt,Reinhold Schmidt,Peter R Schofield,Markus Scholz,Gunter Schumann,Emanuel Schwarz,Li Shen,Jean Shin,Sanjay M Sisodiya,Albert V Smith,Jordan W Smoller,Hilkka S Soininen,Vidar M Steen,Dan J Stein,Jason L Stein,Sophia I Thomopoulos,Arthur W Toga,Diana Tordesillas-Gutiérrez,Julian N Trollor,Maria C Valdes-Hernandez,Dennis van T Ent,Hans van Bokhoven,Dennis van der Meer,Nic J A van der Wee,Javier Vázquez-Bourgon,Dick J Veltman,Meike W Vernooij,Arno Villringer,Louis N Vinke,Henry Völzke,Henrik Walter,Joanna M Wardlaw,Daniel R Weinberger,Michael W Weiner,Wei Wen,Lars T Westlye,Eric Westman,Tonya White,A Veronica Witte,Christiane Wolf,Jingyun Yang,Marcel P Zwiers,M Arfan Ikram,Sudha Seshadri,Paul M Thompson,Claudia L Satizabal,Sarah E Medland,Miguel E Rentería
Source:
Nature genetics
AFM41a: A Novel PAD2 Inhibitor for Sepsis Treatment-Efficacy and Mechanism
lunes, octubre 21, 2024
Author(s):
Tao Dong,Leonard Barasa,Xin Yu,Wenlu Ouyang,Liujiazi Shao,Chao Quan,Su He Wang,Jifeng Zhang,Morgan Salmon,Allan Tsung,Hasan B Alam,Jianjie Ma,Paul R Thompson,Yongqing Li
Source:
International journal of biological sciences
Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries
lunes, octubre 07, 2024
Author(s):
Luis M García-Marín,Adrian I Campos,Santiago Diaz-Torres,Jill A Rabinowitz,Zuriel Ceja,Brittany L Mitchell,Katrina L Grasby,Jackson G Thorp,Ingrid Agartz,Saud Alhusaini,David Ames,Philippe Amouyel,Ole A Andreassen,Konstantinos Arfanakis,Alejandro Arias Vasquez,Nicola J Armstrong,Lavinia Athanasiu,Mark E Bastin,Alexa S Beiser,David A Bennett,Joshua C Bis,Marco Pm Boks,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Jan K Buitelaar,Ralph Burkhardt,Wiepke Cahn,Vince D Calhoun,Owen T Carmichael,Mallar Chakravarty,Qiang Chen,Christopher R K Ching,Sven Cichon,Benedicto Crespo-Facorro,Fabrice Crivello,Anders M Dale,George Davey Smith,Eco Jc de Geus,Philip L De Jager,Greig I de Zubicaray,Stéphanie Debette,Charles DeCarli,Chantal Depondt,Sylvane Desrivières,Srdjan Djurovic,Stefan Ehrlich,Susanne Erk,Thomas Espeseth,Guillén Fernández,Irina Filippi,Simon E Fisher,Debra A Fleischman,Evan Fletcher,Myriam Fornage,Andreas J Forstner,Clyde Francks,Barbara Franke,Tian Ge,Aaron L Goldman,Hans J Grabe,Robert C Green,Oliver Grimm,Nynke A Groenewold,Oliver Gruber,Vilmundur Gudnason,Asta K Håberg,Unn K Haukvik,Andreas Heinz,Derrek P Hibar,Saima Hilal,Jayandra J Himali,Beng-Choon Ho,David F Hoehn,Pieter J Hoekstra,Edith Hofer,Wolfgang Hoffmann,Avram J Holmes,Georg Homuth,Norbert Hosten,M Kamran Ikram,Jonathan C Ipser,Clifford R Jack,Neda Jahanshad,Erik G Jönsson,Rene S Kahn,Ryota Kanai,Marieke Klein,Maria J Knol,Lenore J Launer,Stephen M Lawrie,Stephanie Le Hellard,Phil H Lee,Hervé Lemaître,Shuo Li,David Cm Liewald,Honghuang Lin,W T Longstreth,Oscar L Lopez,Michelle Luciano,Pauline Maillard,Andre F Marquand,Nicholas G Martin,Jean-Luc Martinot,Karen A Mather,Venkata S Mattay,Katie L McMahon,Patrizia Mecocci,Ingrid Melle,Andreas Meyer-Lindenberg,Nazanin Mirza-Schreiber,Yuri Milaneschi,Thomas H Mosley,Thomas W Mühleisen,Bertram Müller-Myhsok,Susana Muñoz Maniega,Matthias Nauck,Kwangsik Nho,Wiro J Niessen,Markus M Nöthen,Paul A Nyquist,Jaap Oosterlaan,Massimo Pandolfo,Tomas Paus,Zdenka Pausova,Brenda Wjh Penninx,G Bruce Pike,Bruce M Psaty,Benno Pütz,Simone Reppermund,Marcella D Rietschel,Shannon L Risacher,Nina Romanczuk-Seiferth,Rafael Romero-Garcia,Gennady V Roshchupkin,Jerome I Rotter,Perminder S Sachdev,Philipp G Sämann,Arvin Saremi,Muralidharan Sargurupremraj,Andrew J Saykin,Lianne Schmaal,Helena Schmidt,Reinhold Schmidt,Peter R Schofield,Markus Scholz,Gunter Schumann,Emanuel Schwarz,Li Shen,Jean Shin,Sanjay M Sisodiya,Albert V Smith,Jordan W Smoller,Hilkka S Soininen,Vidar M Steen,Dan J Stein,Jason L Stein,Sophia I Thomopoulos,Arthur W Toga,Diana Tordesillas-Gutiérrez,Julian N Trollor,Maria C Valdes-Hernandez,Dennis van 't Ent,Hans van Bokhoven,Dennis van der Meer,Nic Ja van der Wee,Javier Vázquez-Bourgon,Dick J Veltman,Meike W Vernooij,Arno Villringer,Louis N Vinke,Henry Völzke,Henrik Walter,Joanna M Wardlaw,Daniel R Weinberger,Michael W Weiner,Wei Wen,Lars T Westlye,Eric Westman,Tonya White,A Veronica Witte,Christiane Wolf,Jingyun Yang,Marcel P Zwiers,M Arfan Ikram,Sudha Seshadri,Paul M Thompson,Claudia L Satizabal,Sarah E Medland,Miguel E Rentería
Source:
medRxiv : the preprint server for health sciences
Muscle-specific pyruvate kinase isoforms, PKM1 and PKM2, regulate mammalian SWI/SNF proteins and histone 3 phosphorylation during myoblast differentiation
miércoles, junio 05, 2024
Author(s):
Monserrat Olea-Flores,Tapan Sharma,Odette Verdejo-Torres,Imaru DiBartolomeo,Paul R Thompson,Teresita Padilla-Benavides,Anthony N Imbalzano
Source:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Muscle-Specific Pyruvate Kinase Isoforms, Pkm1 and Pkm2, Regulate Mammalian SWI/SNF Proteins and Histone 3 Phosphorylation During Myoblast Differentiation
lunes, abril 22, 2024
Author(s):
Monserrat Olea-Flores,Tapan Sharma,Odette Verdejo-Torres,Imaru DiBartolomeo,Paul R Thompson,Teresita Padilla-Benavides,Anthony N Imbalzano
Source:
bioRxiv : the preprint server for biology
Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer
jueves, abril 04, 2024
Author(s):
Alok K Mishra,Tianyi Ye,Shahid Banday,Ritesh P Thakare,Chinh Tran-To Su,Ngoc N H Pham,Amjad Ali,Ankur Kulshreshtha,Shreya Roy Chowdhury,Tessa M Simone,Kai Hu,Lihua Julie Zhu,Birgit Eisenhaber,Sara K Deibler,Karl Simin,Paul R Thompson,Michelle A Kelliher,Frank Eisenhaber,Sunil K Malonia,Michael R Green
Source:
Cell reports
GnRH Induces Citrullination of the Cytoskeleton in Murine Gonadotrope Cells
jueves, marzo 28, 2024
Author(s):
Elizabeth B Quigley,Stanley B DeVore,Shaihla A Khan,Zachary M Geisterfer,Heather M Rothfuss,Ari O Sequoia,Paul R Thompson,Jesse C Gatlin,Brian D Cherrington,Amy M Navratil
Source:
International journal of molecular sciences
PAD2 dysregulation and aberrant protein citrullination feature prominently in reactive astrogliosis and myelin protein aggregation in sporadic ALS
lunes, enero 22, 2024
Author(s):
Issa O Yusuf,Sepideh Parsi,Lyle W Ostrow,Robert H Brown,Paul R Thompson,Zuoshang Xu
Source:
Neurobiology of disease
NET formation is a default epigenetic program controlled by PAD4 in apoptotic neutrophils
miércoles, diciembre 20, 2023
Author(s):
Yanfang Peipei Zhu,Mary Speir,ZheHao Tan,Jamie Casey Lee,Cameron J Nowell,Alyce A Chen,Hajera Amatullah,Ari J Salinger,Carolyn J Huang,Gio Wu,Weiqi Peng,Kasra Askari,Eric Griffis,Majid Ghassemian,Jennifer Santini,Motti Gerlic,William B Kiosses,Sergio D Catz,Hal M Hoffman,Kimberly F Greco,Edie Weller,Paul R Thompson,Lai Ping Wong,Ruslan Sadreyev,Kate L Jeffrey,Ben A Croker
Source:
Science advances
Peptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA
jueves, diciembre 14, 2023
Author(s):
Benjamin Geary,Bo Sun,Ronak R Tilvawala,Leonard Barasa,Konstantin Tsoyi,Ivan O Rosas,Paul R Thompson,I-Cheng Ho
Source:
Frontiers in immunology
Citrullination profile analysis reveals peptidylarginine deaminase 3 as an HSV-1 target to dampen the activity of candidate antiviral restriction factors
miércoles, diciembre 06, 2023
Author(s):
Selina Pasquero,Francesca Gugliesi,Matteo Biolatti,Valentina Dell'Oste,Camilla Albano,Greta Bajetto,Gloria Griffante,Linda Trifirò,Bianca Brugo,Stefano Raviola,Davide Lacarbonara,Qiao Yang,Sen Sudeshna,Leonard Barasa,Hafeez Haniff,Paul R Thompson,Santo Landolfo,Marco De Andrea
Source:
PLoS pathogens
Inhibiting MEK1 R189 citrullination enhances the chemosensitivity of docetaxel to multiple tumour cells
domingo, octubre 01, 2023
Author(s):
Teng Xue,Shujia Fei,Jian Gu,Nan Li,Pengxue Zhang,Xiaoqiu Liu,Paul R Thompson,Xuesen Zhang
Source:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Protein citrullination: inhibition, identification and insertion
domingo, octubre 01, 2023
Author(s):
Leonard Barasa,Paul R Thompson
Source:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels
domingo, septiembre 24, 2023
Author(s):
Janneke Doedée Icso,Paul Ryan Thompson
Source:
The Journal of biological chemistry
Development of LB244, an Irreversible STING Antagonist
lunes, septiembre 11, 2023
Author(s):
Leonard Barasa,Sauradip Chaudhuri,Jeffrey Y Zhou,Zhaozhao Jiang,Shruti Choudhary,Robert Madison Green,Elenore Wiggin,Michael Cameron,Fiachra Humphries,Katherine A Fitzgerald,Paul R Thompson
Source:
Journal of the American Chemical Society
Targeting STING oligomerization with small-molecule inhibitors
lunes, agosto 07, 2023
Author(s):
Fiachra Humphries,Liraz Shmuel-Galia,Zhaozhao Jiang,Jeffrey Y Zhou,Leonard Barasa,Santanu Mondal,Ruth Wilson,Nadia Sultana,Scott A Shaffer,Sze-Ling Ng,G Scott Pesiridis,Paul R Thompson,Katherine A Fitzgerald
Source:
Proceedings of the National Academy of Sciences of the United States of America
SARM1, an Enzyme Involved in Axon Degeneration, Catalyzes Multiple Activities through a Ternary Complex Mechanism
lunes, junio 12, 2023
Author(s):
Janneke D Icso,Leonard Barasa,Paul R Thompson
Source:
Biochemistry
Current insights into the role of citrullination in thrombosis
sábado, mayo 06, 2023
Author(s):
R Madison Green,Paul R Thompson
Source:
Current opinion in chemical biology
Dual Inhibitors of Main Protease (MPro) and Cathepsin L as Potent Antivirals against SARS-CoV2
jueves, noviembre 10, 2022
Author(s):
Santanu Mondal,Yongzhi Chen,Gordon J Lockbaum,Sudeshna Sen,Sauradip Chaudhuri,Archie C Reyes,Jeong Min Lee,Arshia N Kaur,Nadia Sultana,Michael D Cameron,Scott A Shaffer,Celia A Schiffer,Katherine A Fitzgerald,Paul R Thompson
Source:
Journal of the American Chemical Society
Phomoxanthone A Targets ATP Synthase
viernes, septiembre 09, 2022
Author(s):
Rameez Ali,Sangram S Parelkar,Paul R Thompson,Susan Mitroka-Batsford,Siddartha Yerramilli,Suzanne F Scarlata,Katelyn S Mistretta,Jeannine M Coburn,Anita E Mattson
Source:
Chemistry (Weinheim an der Bergstrasse, Germany)
Protein citrullination marks myelin protein aggregation and disease progression in mouse ALS models
jueves, septiembre 08, 2022
Author(s):
Issa O Yusuf,Tao Qiao,Sepideh Parsi,Ronak Tilvawala,Paul R Thompson,Zuoshang Xu
Source:
Acta neuropathologica communications
Carbamylation of Integrin α IIb β 3: The Mechanistic Link to Platelet Dysfunction in ESKD
lunes, agosto 29, 2022
Author(s):
Veronika Binder,Barbara Chruścicka-Smaga,Brith Bergum,Stéphane Jaisson,Philippe Gillery,Joar Sivertsen,Tor Hervig,Marta Kaminska,Ronak Tilvawala,Venkatesh V Nemmara,Paul R Thompson,Jan Potempa,Hans-Peter Marti,Piotr Mydel
Source:
Journal of the American Society of Nephrology : JASN
The chemical biology of NAD+ regulation in axon degeneration
domingo, julio 03, 2022
Author(s):
Janneke D Icso,Paul R Thompson
Source:
Current opinion in chemical biology
Proximity-Dependent Labeling of Cysteines
jueves, noviembre 11, 2021
Author(s):
Sudeshna Sen,Nadia Sultana,Scott A Shaffer,Paul R Thompson
Source:
Journal of the American Chemical Society
Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4
viernes, noviembre 05, 2021
Author(s):
María Teresa Martín Monreal,Alexandra Stripp Rebak,Laura Massarenti,Santanu Mondal,Ladislav Šenolt,Niels Ødum,Michael L Nielsen,Paul R Thompson,Claus H Nielsen,Dres Damgaard
Source:
Frontiers in immunology
Pan-3C Protease Inhibitor Rupintrivir Binds SARS-CoV-2 Main Protease in a Unique Binding Mode
viernes, septiembre 10, 2021
Author(s):
Gordon J Lockbaum,Mina Henes,Jeong Min Lee,Jennifer Timm,Ellen A Nalivaika,Paul R Thompson,Nese Kurt Yilmaz,Celia A Schiffer
Source:
Biochemistry
A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium
jueves, septiembre 09, 2021
Author(s):
Boris A Gutman,Theo G M van Erp,Kathryn Alpert,Christopher R K Ching,Dmitry Isaev,Anjani Ragothaman,Neda Jahanshad,Arvin Saremi,Artemis Zavaliangos-Petropulu,David C Glahn,Li Shen,Shan Cong,Dag Alnaes,Ole Andreas Andreassen,Nhat Trung Doan,Lars T Westlye,Peter Kochunov,Theodore D Satterthwaite,Daniel H Wolf,Alexander J Huang,Charles Kessler,Andrea Weideman,Dana Nguyen,Bryon A Mueller,Lawrence Faziola,Steven G Potkin,Adrian Preda,Daniel H Mathalon,Juan Bustillo,Vince Calhoun,Judith M Ford,Esther Walton,Stefan Ehrlich,Giuseppe Ducci,Nerisa Banaj,Fabrizio Piras,Federica Piras,Gianfranco Spalletta,Erick J Canales-Rodríguez,Paola Fuentes-Claramonte,Edith Pomarol-Clotet,Joaquim Radua,Raymond Salvador,Salvador Sarró,Erin W Dickie,Aristotle Voineskos,Diana Tordesillas-Gutiérrez,Benedicto Crespo-Facorro,Esther Setién-Suero,Jacqueline Mayoral van Son,Stefan Borgwardt,Fabienne Schönborn-Harrisberger,Derek Morris,Gary Donohoe,Laurena Holleran,Dara Cannon,Colm McDonald,Aiden Corvin,Michael Gill,Geraldo Busatto Filho,Pedro G P Rosa,Mauricio H Serpa,Marcus V Zanetti,Irina Lebedeva,Vasily Kaleda,Alexander Tomyshev,Tim Crow,Anthony James,Simon Cervenka,Carl M Sellgren,Helena Fatouros-Bergman,Ingrid Agartz,Fleur Howells,Dan J Stein,Henk Temmingh,Anne Uhlmann,Greig I de Zubicaray,Katie L McMahon,Margie Wright,Derin Cobia,John G Csernansky,Paul M Thompson,Jessica A Turner,Lei Wang
Source:
Human brain mapping
A Streamlined Data Analysis Pipeline for the Identification of Sites of Citrullination
martes, septiembre 07, 2021
Author(s):
Aaron J Maurais,Ari J Salinger,Micaela Tobin,Scott A Shaffer,Eranthie Weerapana,Paul R Thompson
Source:
Biochemistry
The role of SERPIN citrullination in thrombosis
jueves, agosto 05, 2021
Author(s):
Ronak Tilvawala,Venkatesh V Nemmara,Archie C Reyes,Nicoletta Sorvillo,Ari J Salinger,Deya Cherpokova,Saeko Fukui,Sarah Gutch,Denisa Wagner,Paul R Thompson
Source:
Cell chemical biology
PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis
domingo, julio 18, 2021
Author(s):
Bo Sun,Beverly Tomita,Ari Salinger,Ronak R Tilvawala,Ling Li,Hana Hakami,Tao Liu,Konstantin Tsoyi,Ivan O Rosas,Dieter P Reinhardt,Paul R Thompson,I-Cheng Ho
Source:
Matrix biology : journal of the International Society for Matrix Biology
Progesterone stimulates histone citrullination to increase IGFBP1 expression in uterine cells
martes, mayo 25, 2021
Author(s):
Coleman H Young,Bryce Snow,Stanley B DeVore,Adithya Mohandass,Venkatesh V Nemmara,Paul R Thompson,Baskaran Thyagarajan,Amy M Navratil,Brian D Cherrington
Source:
Reproduction (Cambridge, England)
Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design
lunes, mayo 10, 2021
Author(s):
Kazumasa Funabashi,Mizuki Sawata,Anna Nagai,Megumi Akimoto,Ryutaro Mashimo,Hidenari Takahara,Kenji Kizawa,Paul R Thompson,Kenji Ite,Kenichi Kitanishi,Masaki Unno
Source:
Archives of biochemistry and biophysics
Synthesis and Anticancer Activity of Structure Simplified Naturally-Inspired Dimeric Chromenone Derivatives
jueves, abril 08, 2021
Author(s):
Rameez Ali,Yong Guan,Alexandria N Leveille,Elizabeth Vaughn,Sangram Parelkar,Paul R Thompson,Anita E Mattson
Source:
European journal of organic chemistry
1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
martes, marzo 23, 2021
Author(s):
Ida E Sønderby,Dennis van der Meer,Clara Moreau,Tobias Kaufmann,G Bragi Walters,Maria Ellegaard,Abdel Abdellaoui,David Ames,Katrin Amunts,Micael Andersson,Nicola J Armstrong,Manon Bernard,Nicholas B Blackburn,John Blangero,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Robin Bülow,Rune Bøen,Wiepke Cahn,Vince D Calhoun,Svenja Caspers,Christopher R K Ching,Sven Cichon,Simone Ciufolini,Benedicto Crespo-Facorro,Joanne E Curran,Anders M Dale,Shareefa Dalvie,Paola Dazzan,Eco J C de Geus,Greig I de Zubicaray,Sonja M C de Zwarte,Sylvane Desrivieres,Joanne L Doherty,Gary Donohoe,Bogdan Draganski,Stefan Ehrlich,Else Eising,Thomas Espeseth,Kim Fejgin,Simon E Fisher,Tormod Fladby,Oleksandr Frei,Vincent Frouin,Masaki Fukunaga,Thomas Gareau,Tian Ge,David C Glahn,Hans J Grabe,Nynke A Groenewold,Ómar Gústafsson,Jan Haavik,Asta K Haberg,Jeremy Hall,Ryota Hashimoto,Jayne Y Hehir-Kwa,Derrek P Hibar,Manon H J Hillegers,Per Hoffmann,Laurena Holleran,Avram J Holmes,Georg Homuth,Jouke-Jan Hottenga,Hilleke E Hulshoff Pol,Masashi Ikeda,Neda Jahanshad,Christiane Jockwitz,Stefan Johansson,Erik G Jönsson,Niklas R Jørgensen,Masataka Kikuchi,Emma E M Knowles,Kuldeep Kumar,Stephanie Le Hellard,Costin Leu,David E J Linden,Jingyu Liu,Arvid Lundervold,Astri Johansen Lundervold,Anne M Maillard,Nicholas G Martin,Sandra Martin-Brevet,Karen A Mather,Samuel R Mathias,Katie L McMahon,Allan F McRae,Sarah E Medland,Andreas Meyer-Lindenberg,Torgeir Moberget,Claudia Modenato,Jennifer Monereo Sánchez,Derek W Morris,Thomas W Mühleisen,Robin M Murray,Jacob Nielsen,Jan E Nordvik,Lars Nyberg,Loes M Olde Loohuis,Roel A Ophoff,Michael J Owen,Tomas Paus,Zdenka Pausova,Juan M Peralta,G Bruce Pike,Carlos Prieto,Erin B Quinlan,Céline S Reinbold,Tiago Reis Marques,James J H Rucker,Perminder S Sachdev,Sigrid B Sando,Peter R Schofield,Andrew J Schork,Gunter Schumann,Jean Shin,Elena Shumskaya,Ana I Silva,Sanjay M Sisodiya,Vidar M Steen,Dan J Stein,Lachlan T Strike,Ikuo K Suzuki,Christian K Tamnes,Alexander Teumer,Anbupalam Thalamuthu,Diana Tordesillas-Gutiérrez,Anne Uhlmann,Magnus O Ulfarsson,Dennis van 't Ent,Marianne B M van den Bree,Pierre Vanderhaeghen,Evangelos Vassos,Wei Wen,Katharina Wittfeld,Margaret J Wright,Ingrid Agartz,Srdjan Djurovic,Lars T Westlye,Hreinn Stefansson,Kari Stefansson,Sébastien Jacquemont,Paul M Thompson,Ole A Andreassen,ENIGMA-CNV working group
Source:
Translational psychiatry
PADI2-Catalyzed MEK1 Citrullination Activates ERK1/2 and Promotes IGF2BP1-Mediated SOX2 mRNA Stability in Endometrial Cancer
lunes, marzo 22, 2021
Author(s):
Teng Xue,Xiaoqiu Liu,Mei Zhang,Qiukai E,Shuting Liu,Maosheng Zou,Ying Li,Zhinan Ma,Yun Han,Paul Thompson,Xuesen Zhang
Source:
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Citrullinated vimentin mediates development and progression of lung fibrosis
jueves, marzo 18, 2021
Author(s):
Fu Jun Li,Ranu Surolia,Huashi Li,Zheng Wang,Gang Liu,Tejaswini Kulkarni,Adriana V F Massicano,James A Mobley,Santanu Mondal,Joao A de Andrade,Scott A Coonrod,Paul R Thompson,Keith Wille,Suzanne E Lapi,Mohammad Athar,Victor J Thannickal,A Brent Carter,Veena B Antony
Source:
Science translational medicine
Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188
jueves, enero 28, 2021
Author(s):
Gordon J Lockbaum,Archie C Reyes,Jeong Min Lee,Ronak Tilvawala,Ellen A Nalivaika,Akbar Ali,Nese Kurt Yilmaz,Paul R Thompson,Celia A Schiffer
Source:
Viruses
Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice
miércoles, noviembre 18, 2020
Author(s):
Fernanda M C Sodré,Samal Bissenova,Ylke Bruggeman,Ronak Tilvawala,Dana P Cook,Claire Berthault,Santanu Mondal,Aïsha Callebaut,Sylvaine You,Raphael Scharfmann,Roberto Mallone,Paul R Thompson,Chantal Mathieu,Mijke Buitinga,Lut Overbergh
Source:
Diabetes
Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis
jueves, octubre 15, 2020
Author(s):
Yuzi Tian,Shibin Qu,Hasan B Alam,Aaron M Williams,Zhenyu Wu,Qiufang Deng,Baihong Pan,Jing Zhou,Baoling Liu,Xiuzhen Duan,Jianjie Ma,Santanu Mondal,Paul R Thompson,Kathleen A Stringer,Theodore J Standiford,Yongqing Li
Source:
JCI insight
Succination inactivates gasdermin D and blocks pyroptosis
sábado, agosto 22, 2020
Author(s):
Fiachra Humphries,Liraz Shmuel-Galia,Natalia Ketelut-Carneiro,Sheng Li,Bingwei Wang,Venkatesh V Nemmara,Ruth Wilson,Zhaozhao Jiang,Farnaz Khalighinejad,Khaja Muneeruddin,Scott A Shaffer,Ranjan Dutta,Carolina Ionete,Scott Pesiridis,Shuo Yang,Paul R Thompson,Katherine A Fitzgerald
Source:
Science (New York, N.Y.)
Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome
jueves, abril 16, 2020
Author(s):
Guangyuan Li,Coleman H Young,Bryce Snow,Amanda O Christensen,M Kristen Demoruelle,Venkatesh V Nemmara,Paul R Thompson,Heather M Rothfuss,Brian D Cherrington
Source:
International journal of molecular sciences
Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines
jueves, febrero 27, 2020
Author(s):
Pinar Uysal-Onganer,Amy MacLatchy,Rayan Mahmoud,Igor Kraev,Paul R Thompson,Jameel M Inal,Sigrun Lange
Source:
International journal of molecular sciences
Initial Kinetic Characterization of Sterile Alpha and Toll/Interleukin Receptor Motif-Containing Protein 1
jueves, febrero 13, 2020
Author(s):
Heather S Loring,Janneke D Icso,Venkatesh V Nemmara,Paul R Thompson
Source:
Biochemistry
Erratum for Research Article "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis" by C. Carmona-Rivera, P. M. Carlucci, E. Moore, N. Lingampalli, H. Uchtenhagen, E. James, Y. Liu, K. L. Bicker, H. Wahamma, V. Hoffman, A. I. Catrina, P. Thompson, J. H. Buckner, W. H. Robinson, D. A. Fox, M. J. Kaplan
domingo, febrero 02, 2020
Author(s):
Carmelo Carmona-Rivera,Philip M. Carlucci,Erica Moore,Nithya Lingampalli,Hannes Uchtenhagen,Eddie James,Yudong Liu,Kevin L. Bicker,Heidi Wahamaa,Victoria Hoffmann,Anca Irinel Catrina,Paul R. Thompson,Jane H. Buckner,William H. Robinson,David A. Fox,Mariana J. Kaplan
Source:
Science immunology
Emergence of SARM1 as a Potential Therapeutic Target for Wallerian-type Diseases
martes, noviembre 26, 2019
Author(s):
Heather S Loring,Paul R Thompson
Source:
Cell chemical biology
Reciprocal regulation of Th2 and Th17 cells by PAD2-mediated citrullination
viernes, noviembre 15, 2019
Author(s):
Bo Sun,Hui-Hsin Chang,Ari Salinger,Beverly Tomita,Mandar Bawadekar,Caitlyn L Holmes,Miriam A Shelef,Eranthie Weerapana,Paul R Thompson,I-Cheng Ho
Source:
JCI insight
Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition
jueves, octubre 31, 2019
Author(s):
Writing Committee for the ENIGMA-CNV Working Group,Dennis van der Meer,Ida E Sønderby,Tobias Kaufmann,G Bragi Walters,Abdel Abdellaoui,David Ames,Katrin Amunts,Micael Andersson,Nicola J Armstrong,Manon Bernard,Nicholas B Blackburn,John Blangero,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Robin Bülow,Wiepke Cahn,Vince D Calhoun,Svenja Caspers,Gianpiero L Cavalleri,Christopher R K Ching,Sven Cichon,Simone Ciufolini,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E Curran,Shareefa Dalvie,Paola Dazzan,Eco J C de Geus,Greig I de Zubicaray,Sonja M C de Zwarte,Norman Delanty,Anouk den Braber,Sylvane Desrivieres,Marta Di Forti,Joanne L Doherty,Gary Donohoe,Stefan Ehrlich,Else Eising,Thomas Espeseth,Simon E Fisher,Tormod Fladby,Oleksandr Frei,Vincent Frouin,Masaki Fukunaga,Thomas Gareau,David C Glahn,Hans J Grabe,Nynke A Groenewold,Ómar Gústafsson,Jan Haavik,Asta K Haberg,Ryota Hashimoto,Jayne Y Hehir-Kwa,Derrek P Hibar,Manon H J Hillegers,Per Hoffmann,Laurena Holleran,Jouke-Jan Hottenga,Hilleke E Hulshoff Pol,Masashi Ikeda,Sébastien Jacquemont,Neda Jahanshad,Christiane Jockwitz,Stefan Johansson,Erik G Jönsson,Masataka Kikuchi,Emma E M Knowles,John B Kwok,Stephanie Le Hellard,David E J Linden,Jingyu Liu,Arvid Lundervold,Astri J Lundervold,Nicholas G Martin,Karen A Mather,Samuel R Mathias,Katie L McMahon,Allan F McRae,Sarah E Medland,Torgeir Moberget,Clara Moreau,Derek W Morris,Thomas W Mühleisen,Robin M Murray,Jan E Nordvik,Lars Nyberg,Loes M Olde Loohuis,Roel A Ophoff,Michael J Owen,Tomas Paus,Zdenka Pausova,Juan M Peralta,Bruce Pike,Carlos Prieto,Erin Burke Quinlan,Céline S Reinbold,Tiago Reis Marques,James J H Rucker,Perminder S Sachdev,Sigrid B Sando,Peter R Schofield,Andrew J Schork,Gunter Schumann,Jean Shin,Elena Shumskaya,Ana I Silva,Sanjay M Sisodiya,Vidar M Steen,Dan J Stein,Lachlan T Strike,Christian K Tamnes,Alexander Teumer,Anbupalam Thalamuthu,Diana Tordesillas-Gutiérrez,Anne Uhlmann,Magnús Ö Úlfarsson,Dennis van 't Ent,Marianne B M van den Bree,Evangelos Vassos,Wei Wen,Katharina Wittfeld,Margaret J Wright,Tetyana Zayats,Anders M Dale,Srdjan Djurovic,Ingrid Agartz,Lars T Westlye,Hreinn Stefánsson,Kári Stefánsson,Paul M Thompson,Ole A Andreassen
Source:
JAMA psychiatry
Genetic architecture of subcortical brain structures in 38,851 individuals
miércoles, octubre 23, 2019
Author(s):
Claudia L Satizabal,Hieab H H Adams,Derrek P Hibar,Charles C White,Maria J Knol,Jason L Stein,Markus Scholz,Muralidharan Sargurupremraj,Neda Jahanshad,Gennady V Roshchupkin,Albert V Smith,Joshua C Bis,Xueqiu Jian,Michelle Luciano,Edith Hofer,Alexander Teumer,Sven J van der Lee,Jingyun Yang,Lisa R Yanek,Tom V Lee,Shuo Li,Yanhui Hu,Jia Yu Koh,John D Eicher,Sylvane Desrivières,Alejandro Arias-Vasquez,Ganesh Chauhan,Lavinia Athanasiu,Miguel E Rentería,Sungeun Kim,David Hoehn,Nicola J Armstrong,Qiang Chen,Avram J Holmes,Anouk den Braber,Iwona Kloszewska,Micael Andersson,Thomas Espeseth,Oliver Grimm,Lucija Abramovic,Saud Alhusaini,Yuri Milaneschi,Martina Papmeyer,Tomas Axelsson,Stefan Ehrlich,Roberto Roiz-Santiañez,Bernd Kraemer,Asta K Håberg,Hannah J Jones,G Bruce Pike,Dan J Stein,Allison Stevens,Janita Bralten,Meike W Vernooij,Tamara B Harris,Irina Filippi,A Veronica Witte,Tulio Guadalupe,Katharina Wittfeld,Thomas H Mosley,James T Becker,Nhat Trung Doan,Saskia P Hagenaars,Yasaman Saba,Gabriel Cuellar-Partida,Najaf Amin,Saima Hilal,Kwangsik Nho,Nazanin Mirza-Schreiber,Konstantinos Arfanakis,Diane M Becker,David Ames,Aaron L Goldman,Phil H Lee,Dorret I Boomsma,Simon Lovestone,Sudheer Giddaluru,Stephanie Le Hellard,Manuel Mattheisen,Marc M Bohlken,Dalia Kasperaviciute,Lianne Schmaal,Stephen M Lawrie,Ingrid Agartz,Esther Walton,Diana Tordesillas-Gutierrez,Gareth E Davies,Jean Shin,Jonathan C Ipser,Louis N Vinke,Martine Hoogman,Tianye Jia,Ralph Burkhardt,Marieke Klein,Fabrice Crivello,Deborah Janowitz,Owen Carmichael,Unn K Haukvik,Benjamin S Aribisala,Helena Schmidt,Lachlan T Strike,Ching-Yu Cheng,Shannon L Risacher,Benno Pütz,Debra A Fleischman,Amelia A Assareh,Venkata S Mattay,Randy L Buckner,Patrizia Mecocci,Anders M Dale,Sven Cichon,Marco P Boks,Mar Matarin,Brenda W J H Penninx,Vince D Calhoun,M Mallar Chakravarty,Andre F Marquand,Christine Macare,Shahrzad Kharabian Masouleh,Jaap Oosterlaan,Philippe Amouyel,Katrin Hegenscheid,Jerome I Rotter,Andrew J Schork,David C M Liewald,Greig I de Zubicaray,Tien Yin Wong,Li Shen,Philipp G Sämann,Henry Brodaty,Joshua L Roffman,Eco J C de Geus,Magda Tsolaki,Susanne Erk,Kristel R van Eijk,Gianpiero L Cavalleri,Nic J A van der Wee,Andrew M McIntosh,Randy L Gollub,Kazima B Bulayeva,Manon Bernard,Jennifer S Richards,Jayandra J Himali,Markus Loeffler,Nanda Rommelse,Wolfgang Hoffmann,Lars T Westlye,Maria C Valdés Hernández,Narelle K Hansell,Theo G M van Erp,Christiane Wolf,John B J Kwok,Bruno Vellas,Andreas Heinz,Loes M Olde Loohuis,Norman Delanty,Beng-Choon Ho,Christopher R K Ching,Elena Shumskaya,Baljeet Singh,Albert Hofman,Dennis van der Meer,Georg Homuth,Bruce M Psaty,Mark E Bastin,Grant W Montgomery,Tatiana M Foroud,Simone Reppermund,Jouke-Jan Hottenga,Andrew Simmons,Andreas Meyer-Lindenberg,Wiepke Cahn,Christopher D Whelan,Marjolein M J van Donkelaar,Qiong Yang,Norbert Hosten,Robert C Green,Anbupalam Thalamuthu,Sebastian Mohnke,Hilleke E Hulshoff Pol,Honghuang Lin,Clifford R Jack,Peter R Schofield,Thomas W Mühleisen,Pauline Maillard,Steven G Potkin,Wei Wen,Evan Fletcher,Arthur W Toga,Oliver Gruber,Matthew Huentelman,George Davey Smith,Lenore J Launer,Lars Nyberg,Erik G Jönsson,Benedicto Crespo-Facorro,Nastassja Koen,Douglas N Greve,André G Uitterlinden,Daniel R Weinberger,Vidar M Steen,Iryna O Fedko,Nynke A Groenewold,Wiro J Niessen,Roberto Toro,Christophe Tzourio,William T Longstreth,M Kamran Ikram,Jordan W Smoller,Marie-Jose van Tol,Jessika E Sussmann,Tomas Paus,Hervé Lemaître,Matthias L Schroeter,Bernard Mazoyer,Ole A Andreassen,Florian Holsboer,Chantal Depondt,Dick J Veltman,Jessica A Turner,Zdenka Pausova,Gunter Schumann,Daan van Rooij,Srdjan Djurovic,Ian J Deary,Katie L McMahon,Bertram Müller-Myhsok,Rachel M Brouwer,Hilkka Soininen,Massimo Pandolfo,Thomas H Wassink,Joshua W Cheung,Thomas Wolfers,Jean-Luc Martinot,Marcel P Zwiers,Matthias Nauck,Ingrid Melle,Nicholas G Martin,Ryota Kanai,Eric Westman,René S Kahn,Sanjay M Sisodiya,Tonya White,Arvin Saremi,Hans van Bokhoven,Han G Brunner,Henry Völzke,Margaret J Wright,Dennis van 't Ent,Markus M Nöthen,Roel A Ophoff,Jan K Buitelaar,Guillén Fernández,Perminder S Sachdev,Marcella Rietschel,Neeltje E M van Haren,Simon E Fisher,Alexa S Beiser,Clyde Francks,Andrew J Saykin,Karen A Mather,Nina Romanczuk-Seiferth,Catharina A Hartman,Anita L DeStefano,Dirk J Heslenfeld,Michael W Weiner,Henrik Walter,Pieter J Hoekstra,Paul A Nyquist,Barbara Franke,David A Bennett,Hans J Grabe,Andrew D Johnson,Christopher Chen,Cornelia M van Duijn,Oscar L Lopez,Myriam Fornage,Joanna M Wardlaw,Reinhold Schmidt,Charles DeCarli,Philip L De Jager,Arno Villringer,Stéphanie Debette,Vilmundur Gudnason,Sarah E Medland,Joshua M Shulman,Paul M Thompson,Sudha Seshadri,M Arfan Ikram
Source:
Nature genetics
Inhibiting PAD2 enhances the anti-tumor effect of docetaxel in tamoxifen-resistant breast cancer cells
sábado, octubre 12, 2019
Author(s):
Fujun Li,Lixia Miao,Teng Xue,Hao Qin,Santanu Mondal,Paul R Thompson,Scott A Coonrod,Xiaoqiu Liu,Xuesen Zhang
Source:
Journal of experimental & clinical cancer research : CR
Cutting Edge: Protein Arginine Deiminase 2 and 4 Regulate NLRP3 Inflammasome-Dependent IL-1β Maturation and ASC Speck Formation in Macrophages
viernes, julio 12, 2019
Author(s):
Neha Mishra,Lidja Schwerdtner,Kelly Sams,Santanu Mondal,Fareed Ahmad,Reinhold E Schmidt,Scott A Coonrod,Paul R Thompson,Markus M Lerch,Lukas Bossaller
Source:
Journal of immunology (Baltimore, Md. : 1950)
Halogen Bonding Increases the Potency and Isozyme Selectivity of Protein Arginine Deiminase 1 Inhibitors
sábado, julio 06, 2019
Author(s):
Santanu Mondal,Xuefeng Gong,Xiaoqian Zhang,Ari J Salinger,Li Zheng,Sudeshna Sen,Eranthie Weerapana,Xuesen Zhang,Paul R Thompson
Source:
Angewandte Chemie (International ed. in English)
Calcium Regulates the Nuclear Localization of Protein Arginine Deiminase 2
viernes, junio 28, 2019
Author(s):
Li Zheng,Mitesh Nagar,Aaron J Maurais,Daniel J Slade,Sangram S Parelkar,Scott A Coonrod,Eranthie Weerapana,Paul R Thompson
Source:
Biochemistry
Development of a Suicide Inhibition-Based Protein Labeling Strategy for Nicotinamide N-Methyltransferase
martes, abril 02, 2019
Author(s):
Sudeshna Sen,Santanu Mondal,Li Zheng,Ari J Salinger,Walter Fast,Eranthie Weerapana,Paul R Thompson
Source:
ACS chemical biology
Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis
lunes, marzo 18, 2019
Author(s):
Laura Cau,Hidenari Takahara,Paul R Thompson,Guy Serre,Marie-Claire Méchin,Michel Simon
Source:
The Journal of investigative dermatology
Thioredoxin Modulates Protein Arginine Deiminase 4 (PAD4)-Catalyzed Citrullination
martes, marzo 12, 2019
Author(s):
Mitesh Nagar,Ronak Tilvawala,Paul R Thompson
Source:
Frontiers in immunology
Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination
viernes, marzo 08, 2019
Author(s):
Santanu Mondal,Paul R Thompson
Source:
Accounts of chemical research
Peptidyl arginine deiminases: detection and functional analysis of protein citrullination
miércoles, marzo 06, 2019
Author(s):
Ronak Tilvawala,Paul R Thompson
Source:
Current opinion in structural biology
Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
sábado, febrero 02, 2019
Author(s):
Ida E Sønderby,Ómar Gústafsson,Nhat Trung Doan,Derrek P Hibar,Sandra Martin-Brevet,Abdel Abdellaoui,David Ames,Katrin Amunts,Michael Andersson,Nicola J Armstrong,Manon Bernard,Nicholas Blackburn,John Blangero,Dorret I Boomsma,Janita Bralten,Hans-Richard Brattbak,Henry Brodaty,Rachel M Brouwer,Robin Bülow,Vince Calhoun,Svenja Caspers,Gianpiero Cavalleri,Chi-Hua Chen,Sven Cichon,Simone Ciufolini,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E Curran,Anders M Dale,Shareefa Dalvie,Paola Dazzan,Eco J C de Geus,Greig I de Zubicaray,Sonja M C de Zwarte,Norman Delanty,Anouk den Braber,Sylvane Desrivières,Gary Donohoe,Bogdan Draganski,Stefan Ehrlich,Thomas Espeseth,Simon E Fisher,Barbara Franke,Vincent Frouin,Masaki Fukunaga,Thomas Gareau,David C Glahn,Hans Grabe,Nynke A Groenewold,Jan Haavik,Asta Håberg,Ryota Hashimoto,Jayne Y Hehir-Kwa,Andreas Heinz,Manon H J Hillegers,Per Hoffmann,Laurena Holleran,Jouke-Jan Hottenga,Hilleke E Hulshoff,Masashi Ikeda,Neda Jahanshad,Terry Jernigan,Christiane Jockwitz,Stefan Johansson,Gudrun A Jonsdottir,Erik G Jönsson,Rene Kahn,Tobias Kaufmann,Sinead Kelly,Masataka Kikuchi,Emma E M Knowles,Knut K Kolskår,John B Kwok,Stephanie Le Hellard,Costin Leu,Jingyu Liu,Astri J Lundervold,Arvid Lundervold,Nicholas G Martin,Karen Mather,Samuel R Mathias,Mark McCormack,Katie L McMahon,Allan McRae,Yuri Milaneschi,Clara Moreau,Derek Morris,David Mothersill,Thomas W Mühleisen,Robin Murray,Jan E Nordvik,Lars Nyberg,Loes M Olde Loohuis,Roel Ophoff,Tomas Paus,Zdenka Pausova,Brenda Penninx,Juan M Peralta,Bruce Pike,Carlos Prieto,Sara Pudas,Erin Quinlan,Daniel S Quintana,Céline S Reinbold,Tiago Reis Marques,Alexandre Reymond,Genevieve Richard,Borja Rodriguez-Herreros,Roberto Roiz-Santiañez,Jarek Rokicki,James Rucker,Perminder Sachdev,Anne-Marthe Sanders,Sigrid B Sando,Lianne Schmaal,Peter R Schofield,Andrew J Schork,Gunter Schumann,Jean Shin,Elena Shumskaya,Sanjay Sisodiya,Vidar M Steen,Dan J Stein,Stacy Steinberg,Lachlan Strike,Alexander Teumer,Anbu Thalamuthu,Diana Tordesillas-Gutierrez,Jessica Turner,Torill Ueland,Anne Uhlmann,Magnus O Ulfarsson,Dennis van 't Ent,Dennis van der Meer,Neeltje E M van Haren,Anja Vaskinn,Evangelos Vassos,G Bragi Walters,Yunpeng Wang,Wei Wen,Christopher D Whelan,Katharina Wittfeld,Margie Wright,Hidenaga Yamamori,Tetyana Zayats,Ingrid Agartz,Lars T Westlye,Sébastien Jacquemont,Srdjan Djurovic,Hreinn Stefánsson,Kári Stefánsson,Paul Thompson,Ole A Andreassen,16p11.2 European Consortium, for the ENIGMA-CNV working group
Source:
Molecular psychiatry
Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
viernes, octubre 05, 2018
Author(s):
Ida E Sønderby,Ómar Gústafsson,Nhat Trung Doan,Derrek P Hibar,Sandra Martin-Brevet,Abdel Abdellaoui,David Ames,Katrin Amunts,Michael Andersson,Nicola J Armstrong,Manon Bernard,Nicholas Blackburn,John Blangero,Dorret I Boomsma,Janita Bralten,Hans-Richard Brattbak,Henry Brodaty,Rachel M Brouwer,Robin Bülow,Vince Calhoun,Svenja Caspers,Gianpiero Cavalleri,Chi-Hua Chen,Sven Cichon,Simone Ciufolini,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E Curran,Anders M Dale,Shareefa Dalvie,Paola Dazzan,Eco J C de Geus,Greig I de Zubicaray,Sonja M C de Zwarte,Norman Delanty,Anouk den Braber,Sylvane Desrivières,Gary Donohoe,Bogdan Draganski,Stefan Ehrlich,Thomas Espeseth,Simon E Fisher,Barbara Franke,Vincent Frouin,Masaki Fukunaga,Thomas Gareau,David C Glahn,Hans Grabe,Nynke A Groenewold,Jan Haavik,Asta Håberg,Ryota Hashimoto,Jayne Y Hehir-Kwa,Andreas Heinz,Manon H J Hillegers,Per Hoffmann,Laurena Holleran,Jouke-Jan Hottenga,Hilleke E Hulshoff,Masashi Ikeda,Neda Jahanshad,Terry Jernigan,Christiane Jockwitz,Stefan Johansson,Gudrun A Jonsdottir,Erik G Jönsson,Rene Kahn,Tobias Kaufmann,Sinead Kelly,Masataka Kikuchi,Emma E M Knowles,Knut K Kolskår,John B Kwok,Stephanie Le Hellard,Costin Leu,Jingyu Liu,Astri J Lundervold,Arvid Lundervold,Nicholas G Martin,Karen Mather,Samuel R Mathias,Mark McCormack,Katie L McMahon,Allan McRae,Yuri Milaneschi,Clara Moreau,Derek Morris,David Mothersill,Thomas W Mühleisen,Robin Murray,Jan E Nordvik,Lars Nyberg,Loes M Olde Loohuis,Roel Ophoff,Tomas Paus,Zdenka Pausova,Brenda Penninx,Juan M Peralta,Bruce Pike,Carlos Prieto,Sara Pudas,Erin Quinlan,Daniel S Quintana,Céline S Reinbold,Tiago Reis Marques,Alexandre Reymond,Genevieve Richard,Borja Rodriguez-Herreros,Roberto Roiz-Santiañez,Jarek Rokicki,James Rucker,Perminder Sachdev,Anne-Marthe Sanders,Sigrid B Sando,Lianne Schmaal,Peter R Schofield,Andrew J Schork,Gunter Schumann,Jean Shin,Elena Shumskaya,Sanjay Sisodiya,Vidar M Steen,Dan J Stein,Stacy Steinberg,Lachlan Strike,Alexander Teumer,Anbu Thalamuthu,Diana Tordesillas-Gutierrez,Jessica Turner,Torill Ueland,Anne Uhlmann,Magnus O Ulfarsson,Dennis van 't Ent,Dennis van der Meer,Neeltje E M van Haren,Anja Vaskinn,Evangelos Vassos,G Bragi Walters,Yunpeng Wang,Wei Wen,Christopher D Whelan,Katharina Wittfeld,Margie Wright,Hidenaga Yamamori,Tetyana Zayats,Ingrid Agartz,Lars T Westlye,Sébastien Jacquemont,Srdjan Djurovic,Hreinn Stefánsson,Kári Stefánsson,Paul Thompson,Ole A Andreassen,16p11.2 European Consortium, for the ENIGMA-CNV working group
Source:
Molecular psychiatry
Development of Activity-Based Proteomic Probes for Protein Citrullination
miércoles, septiembre 12, 2018
Author(s):
Venkatesh V Nemmara,Paul R Thompson
Source:
Current topics in microbiology and immunology
Kinetic Mechanism of Nicotinamide N-Methyltransferase
martes, agosto 28, 2018
Author(s):
Heather S Loring,Paul R Thompson
Source:
Biochemistry
Citrullination Inactivates Nicotinamide- N-methyltransferase
jueves, julio 26, 2018
Author(s):
Venkatesh V Nemmara,Ronak Tilvawala,Ari J Salinger,Lacey Miller,Son Hong Nguyen,Eranthie Weerapana,Paul R Thompson
Source:
ACS chemical biology
Histone Citrullination Represses MicroRNA Expression, Resulting in Increased Oncogene mRNAs in Somatolactotrope Cells
miércoles, julio 11, 2018
Author(s):
Stanley B DeVore,Coleman H Young,Guangyuan Li,Anitha Sundararajan,Thiruvarangan Ramaraj,Joann Mudge,Faye Schilkey,Aaron Muth,Paul R Thompson,Brian D Cherrington
Source:
Molecular and cellular biology
Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium
lunes, julio 02, 2018
Author(s):
Theo G M van Erp,Esther Walton,Derrek P Hibar,Lianne Schmaal,Wenhao Jiang,David C Glahn,Godfrey D Pearlson,Nailin Yao,Masaki Fukunaga,Ryota Hashimoto,Naohiro Okada,Hidenaga Yamamori,Juan R Bustillo,Vincent P Clark,Ingrid Agartz,Bryon A Mueller,Wiepke Cahn,Sonja M C de Zwarte,Hilleke E Hulshoff Pol,René S Kahn,Roel A Ophoff,Neeltje E M van Haren,Ole A Andreassen,Anders M Dale,Nhat Trung Doan,Tiril P Gurholt,Cecilie B Hartberg,Unn K Haukvik,Kjetil N Jørgensen,Trine V Lagerberg,Ingrid Melle,Lars T Westlye,Oliver Gruber,Bernd Kraemer,Anja Richter,David Zilles,Vince D Calhoun,Benedicto Crespo-Facorro,Roberto Roiz-Santiañez,Diana Tordesillas-Gutiérrez,Carmel Loughland,Vaughan J Carr,Stanley Catts,Vanessa L Cropley,Janice M Fullerton,Melissa J Green,Frans A Henskens,Assen Jablensky,Rhoshel K Lenroot,Bryan J Mowry,Patricia T Michie,Christos Pantelis,Yann Quidé,Ulrich Schall,Rodney J Scott,Murray J Cairns,Marc Seal,Paul A Tooney,Paul E Rasser,Gavin Cooper,Cynthia Shannon Weickert,Thomas W Weickert,Derek W Morris,Elliot Hong,Peter Kochunov,Lauren M Beard,Raquel E Gur,Ruben C Gur,Theodore D Satterthwaite,Daniel H Wolf,Aysenil Belger,Gregory G Brown,Judith M Ford,Fabio Macciardi,Daniel H Mathalon,Daniel S O'Leary,Steven G Potkin,Adrian Preda,James Voyvodic,Kelvin O Lim,Sarah McEwen,Fude Yang,Yunlong Tan,Shuping Tan,Zhiren Wang,Fengmei Fan,Jingxu Chen,Hong Xiang,Shiyou Tang,Hua Guo,Ping Wan,Dong Wei,Henry J Bockholt,Stefan Ehrlich,Rick P F Wolthusen,Margaret D King,Jody M Shoemaker,Scott R Sponheim,Lieuwe De Haan,Laura Koenders,Marise W Machielsen,Therese van Amelsvoort,Dick J Veltman,Francesca Assogna,Nerisa Banaj,Pietro de Rossi,Mariangela Iorio,Fabrizio Piras,Gianfranco Spalletta,Peter J McKenna,Edith Pomarol-Clotet,Raymond Salvador,Aiden Corvin,Gary Donohoe,Sinead Kelly,Christopher D Whelan,Erin W Dickie,David Rotenberg,Aristotle N Voineskos,Simone Ciufolini,Joaquim Radua,Paola Dazzan,Robin Murray,Tiago Reis Marques,Andrew Simmons,Stefan Borgwardt,Laura Egloff,Fabienne Harrisberger,Anita Riecher-Rössler,Renata Smieskova,Kathryn I Alpert,Lei Wang,Erik G Jönsson,Sanne Koops,Iris E C Sommer,Alessandro Bertolino,Aurora Bonvino,Annabella Di Giorgio,Emma Neilson,Andrew R Mayer,Julia M Stephen,Jun Soo Kwon,Je-Yeon Yun,Dara M Cannon,Colm McDonald,Irina Lebedeva,Alexander S Tomyshev,Tolibjohn Akhadov,Vasily Kaleda,Helena Fatouros-Bergman,Lena Flyckt,Karolinska Schizophrenia Project,Geraldo F Busatto,Pedro G P Rosa,Mauricio H Serpa,Marcus V Zanetti,Cyril Hoschl,Antonin Skoch,Filip Spaniel,David Tomecek,Saskia P Hagenaars,Andrew M McIntosh,Heather C Whalley,Stephen M Lawrie,Christian Knöchel,Viola Oertel-Knöchel,Michael Stäblein,Fleur M Howells,Dan J Stein,Henk S Temmingh,Anne Uhlmann,Carlos Lopez-Jaramillo,Danai Dima,Agnes McMahon,Joshua I Faskowitz,Boris A Gutman,Neda Jahanshad,Paul M Thompson,Jessica A Turner
Source:
Biological psychiatry
Donated chemical probes for open science
sábado, abril 21, 2018
Author(s):
Susanne Müller,Suzanne Ackloo,Cheryl H Arrowsmith,Marcus Bauser,Jeremy L Baryza,Julian Blagg,Jark Böttcher,Chas Bountra,Peter J Brown,Mark E Bunnage,Adrian J Carter,David Damerell,Volker Dötsch,David H Drewry,Aled M Edwards,James Edwards,Jon M Elkins,Christian Fischer,Stephen V Frye,Andreas Gollner,Charles E Grimshaw,Adriaan IJzerman,Thomas Hanke,Ingo V Hartung,Steve Hitchcock,Trevor Howe,Terry V Hughes,Stefan Laufer,Volkhart Mj Li,Spiros Liras,Brian D Marsden,Hisanori Matsui,John Mathias,Ronan C O'Hagan,Dafydd R Owen,Vineet Pande,Daniel Rauh,Saul H Rosenberg,Bryan L Roth,Natalie S Schneider,Cora Scholten,Kumar Singh Saikatendu,Anton Simeonov,Masayuki Takizawa,Chris Tse,Paul R Thompson,Daniel K Treiber,Amélia Yi Viana,Carrow I Wells,Timothy M Willson,William J Zuercher,Stefan Knapp,Anke Mueller-Fahrnow
Source:
eLife
BB-Cl-Amidine as a novel therapeutic for canine and feline mammary cancer via activation of the endoplasmic reticulum stress pathway
sábado, abril 14, 2018
Author(s):
Melissa M Ledet,Robyn Anderson,Rebecca Harman,Aaron Muth,Paul R Thompson,Scott A Coonrod,Gerlinde R Van de Walle
Source:
BMC cancer
The Rheumatoid Arthritis-Associated Citrullinome
martes, abril 10, 2018
Author(s):
Ronak Tilvawala,Son Hong Nguyen,Aaron J Maurais,Venkatesh V Nemmara,Mitesh Nagar,Ari J Salinger,Sunil Nagpal,Eranthie Weerapana,Paul R Thompson
Source:
Cell chemical biology
Response to comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis"
domingo, abril 01, 2018
Author(s):
Carmelo Carmona-Rivera,Kevin L Bicker,Paul R Thompson,Jane H Buckner,William H Robinson,David A Fox,Mariana J Kaplan
Source:
Science immunology
Citrullination regulates the expression of insulin-like growth factor-binding protein 1 (IGFBP1) in ovine uterine luminal epithelial cells
viernes, marzo 23, 2018
Author(s):
Coleman H Young,Heather M Rothfuss,Philip F Gard,Aaron Muth,Paul R Thompson,Ryan L Ashley,Brian D Cherrington
Source:
Reproduction (Cambridge, England)
Photochemical Control of Protein Arginine Deiminase (PAD) Activity
viernes, marzo 09, 2018
Author(s):
Santanu Mondal,Sangram S Parelkar,Mitesh Nagar,Paul R Thompson
Source:
ACS chemical biology
The Development of Benzimidazole-Based Clickable Probes for the Efficient Labeling of Cellular Protein Arginine Deiminases (PADs)
jueves, enero 18, 2018
Author(s):
Venkatesh V Nemmara,Venkataraman Subramanian,Aaron Muth,Santanu Mondal,Ari J Salinger,Aaron J Maurais,Ronak Tilvawala,Eranthie Weerapana,Paul R Thompson
Source:
ACS chemical biology
PAD1 promotes epithelial-mesenchymal transition and metastasis in triple-negative breast cancer cells by regulating MEK1-ERK1/2-MMP2 signaling
martes, agosto 29, 2017
Author(s):
Hao Qin,Xiaoqiu Liu,Fujun Li,Lixia Miao,Tingting Li,Boqun Xu,Xiaofei An,Aaron Muth,Paul R Thompson,Scott A Coonrod,Xuesen Zhang
Source:
Cancer letters
Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα
martes, agosto 08, 2017
Author(s):
Bo Sun,Nishant Dwivedi,Tyler J Bechtel,Janet L Paulsen,Aaron Muth,Mandar Bawadekar,Gang Li,Paul R Thompson,Miriam A Shelef,Celia A Schiffer,Eranthie Weerapana,I-Cheng Ho
Source:
Science immunology
Diverse stimuli engage different neutrophil extracellular trap pathways
sábado, junio 03, 2017
Author(s):
Elaine F Kenny,Alf Herzig,Renate Krüger,Aaron Muth,Santanu Mondal,Paul R Thompson,Volker Brinkmann,Horst von Bernuth,Arturo Zychlinsky
Source:
eLife
Role of peptidylarginine deiminase 2 (PAD2) in mammary carcinoma cell migration
domingo, mayo 28, 2017
Author(s):
Sachi Horibata,Katherine E Rogers,David Sadegh,Lynne J Anguish,John L McElwee,Pragya Shah,Paul R Thompson,Scott A Coonrod
Source:
BMC cancer
Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy
miércoles, mayo 10, 2017
Author(s):
Uchini S Kosgodage,Rita P Trindade,Paul R Thompson,Jameel M Inal,Sigrun Lange
Source:
International journal of molecular sciences
Citrullination/Methylation Crosstalk on Histone H3 Regulates ER-Target Gene Transcription
miércoles, mayo 10, 2017
Author(s):
Kathleen W Clancy,Anna-Maria Russell,Venkataraman Subramanian,Hannah Nguyen,Yuewei Qian,Robert M Campbell,Paul R Thompson
Source:
ACS chemical biology
Development of a Selective Inhibitor of Protein Arginine Deiminase 2
jueves, marzo 23, 2017
Author(s):
Aaron Muth,Venkataraman Subramanian,Edward Beaumont,Mitesh Nagar,Philip Kerry,Paul McEwan,Hema Srinath,Kathleen Clancy,Sangram Parelkar,Paul R Thompson
Source:
Journal of medicinal chemistry
Lowering relative humidity level increases epidermal protein deimination and drives human filaggrin breakdown
miércoles, marzo 01, 2017
Author(s):
Laura Cau,Valérie Pendaries,Emeline Lhuillier,Paul R Thompson,Guy Serre,Hidenari Takahara,Marie-Claire Méchin,Michel Simon
Source:
Journal of dermatological science
Novel genetic loci associated with hippocampal volume
jueves, enero 19, 2017
Author(s):
Derrek P Hibar,Hieab H H Adams,Neda Jahanshad,Ganesh Chauhan,Jason L Stein,Edith Hofer,Miguel E Renteria,Joshua C Bis,Alejandro Arias-Vasquez,M Kamran Ikram,Sylvane Desrivières,Meike W Vernooij,Lucija Abramovic,Saud Alhusaini,Najaf Amin,Micael Andersson,Konstantinos Arfanakis,Benjamin S Aribisala,Nicola J Armstrong,Lavinia Athanasiu,Tomas Axelsson,Ashley H Beecham,Alexa Beiser,Manon Bernard,Susan H Blanton,Marc M Bohlken,Marco P Boks,Janita Bralten,Adam M Brickman,Owen Carmichael,M Mallar Chakravarty,Qiang Chen,Christopher R K Ching,Vincent Chouraki,Gabriel Cuellar-Partida,Fabrice Crivello,Anouk Den Braber,Nhat Trung Doan,Stefan Ehrlich,Sudheer Giddaluru,Aaron L Goldman,Rebecca F Gottesman,Oliver Grimm,Michael E Griswold,Tulio Guadalupe,Boris A Gutman,Johanna Hass,Unn K Haukvik,David Hoehn,Avram J Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Kjetil N Jørgensen,Nazanin Karbalai,Dalia Kasperaviciute,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil H Lee,David C M Liewald,Lorna M Lopez,Michelle Luciano,Christine Macare,Andre F Marquand,Mar Matarin,Karen A Mather,Manuel Mattheisen,David R McKay,Yuri Milaneschi,Susana Muñoz Maniega,Kwangsik Nho,Allison C Nugent,Paul Nyquist,Loes M Olde Loohuis,Jaap Oosterlaan,Martina Papmeyer,Lukas Pirpamer,Benno Pütz,Adaikalavan Ramasamy,Jennifer S Richards,Shannon L Risacher,Roberto Roiz-Santiañez,Nanda Rommelse,Stefan Ropele,Emma J Rose,Natalie A Royle,Tatjana Rundek,Philipp G Sämann,Arvin Saremi,Claudia L Satizabal,Lianne Schmaal,Andrew J Schork,Li Shen,Jean Shin,Elena Shumskaya,Albert V Smith,Emma Sprooten,Lachlan T Strike,Alexander Teumer,Diana Tordesillas-Gutierrez,Roberto Toro,Daniah Trabzuni,Stella Trompet,Dhananjay Vaidya,Jeroen Van der Grond,Sven J Van der Lee,Dennis Van der Meer,Marjolein M J Van Donkelaar,Kristel R Van Eijk,Theo G M Van Erp,Daan Van Rooij,Esther Walton,Lars T Westlye,Christopher D Whelan,Beverly G Windham,Anderson M Winkler,Katharina Wittfeld,Girma Woldehawariat,Christiane Wolf,Thomas Wolfers,Lisa R Yanek,Jingyun Yang,Alex Zijdenbos,Marcel P Zwiers,Ingrid Agartz,Laura Almasy,David Ames,Philippe Amouyel,Ole A Andreassen,Sampath Arepalli,Amelia A Assareh,Sandra Barral,Mark E Bastin,Diane M Becker,James T Becker,David A Bennett,John Blangero,Hans van Bokhoven,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Han G Brunner,Randy L Buckner,Jan K Buitelaar,Kazima B Bulayeva,Wiepke Cahn,Vince D Calhoun,Dara M Cannon,Gianpiero L Cavalleri,Ching-Yu Cheng,Sven Cichon,Mark R Cookson,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E Curran,Michael Czisch,Anders M Dale,Gareth E Davies,Anton J M De Craen,Eco J C De Geus,Philip L De Jager,Greig I De Zubicaray,Ian J Deary,Stéphanie Debette,Charles DeCarli,Norman Delanty,Chantal Depondt,Anita DeStefano,Allissa Dillman,Srdjan Djurovic,Gary Donohoe,Wayne C Drevets,Ravi Duggirala,Thomas D Dyer,Christian Enzinger,Susanne Erk,Thomas Espeseth,Iryna O Fedko,Guillén Fernández,Luigi Ferrucci,Simon E Fisher,Debra A Fleischman,Ian Ford,Myriam Fornage,Tatiana M Foroud,Peter T Fox,Clyde Francks,Masaki Fukunaga,J Raphael Gibbs,David C Glahn,Randy L Gollub,Harald H H Göring,Robert C Green,Oliver Gruber,Vilmundur Gudnason,Sebastian Guelfi,Asta K Håberg,Narelle K Hansell,John Hardy,Catharina A Hartman,Ryota Hashimoto,Katrin Hegenscheid,Andreas Heinz,Stephanie Le Hellard,Dena G Hernandez,Dirk J Heslenfeld,Beng-Choon Ho,Pieter J Hoekstra,Wolfgang Hoffmann,Albert Hofman,Florian Holsboer,Georg Homuth,Norbert Hosten,Jouke-Jan Hottenga,Matthew Huentelman,Hilleke E Hulshoff Pol,Masashi Ikeda,Clifford R Jack,Mark Jenkinson,Robert Johnson,Erik G Jönsson,J Wouter Jukema,René S Kahn,Ryota Kanai,Iwona Kloszewska,David S Knopman,Peter Kochunov,John B Kwok,Stephen M Lawrie,Hervé Lemaître,Xinmin Liu,Dan L Longo,Oscar L Lopez,Simon Lovestone,Oliver Martinez,Jean-Luc Martinot,Venkata S Mattay,Colm McDonald,Andrew M McIntosh,Francis J McMahon,Katie L McMahon,Patrizia Mecocci,Ingrid Melle,Andreas Meyer-Lindenberg,Sebastian Mohnke,Grant W Montgomery,Derek W Morris,Thomas H Mosley,Thomas W Mühleisen,Bertram Müller-Myhsok,Michael A Nalls,Matthias Nauck,Thomas E Nichols,Wiro J Niessen,Markus M Nöthen,Lars Nyberg,Kazutaka Ohi,Rene L Olvera,Roel A Ophoff,Massimo Pandolfo,Tomas Paus,Zdenka Pausova,Brenda W J H Penninx,G Bruce Pike,Steven G Potkin,Bruce M Psaty,Simone Reppermund,Marcella Rietschel,Joshua L Roffman,Nina Romanczuk-Seiferth,Jerome I Rotter,Mina Ryten,Ralph L Sacco,Perminder S Sachdev,Andrew J Saykin,Reinhold Schmidt,Helena Schmidt,Peter R Schofield,Sigurdur Sigursson,Andrew Simmons,Andrew Singleton,Sanjay M Sisodiya,Colin Smith,Jordan W Smoller,Hilkka Soininen,Vidar M Steen,David J Stott,Jessika E Sussmann,Anbupalam Thalamuthu,Arthur W Toga,Bryan J Traynor,Juan Troncoso,Magda Tsolaki,Christophe Tzourio,Andre G Uitterlinden,Maria C Valdés Hernández,Marcel Van der Brug,Aad van der Lugt,Nic J A van der Wee,Neeltje E M Van Haren,Dennis van 't Ent,Marie-Jose Van Tol,Badri N Vardarajan,Bruno Vellas,Dick J Veltman,Henry Völzke,Henrik Walter,Joanna M Wardlaw,Thomas H Wassink,Michael E Weale,Daniel R Weinberger,Michael W Weiner,Wei Wen,Eric Westman,Tonya White,Tien Y Wong,Clinton B Wright,Ronald H Zielke,Alan B Zonderman,Nicholas G Martin,Cornelia M Van Duijn,Margaret J Wright,W T Longstreth,Gunter Schumann,Hans J Grabe,Barbara Franke,Lenore J Launer,Sarah E Medland,Sudha Seshadri,Paul M Thompson,M Arfan Ikram
Source:
Nature communications
Peptidylarginine deiminase 1-catalyzed histone citrullination is essential for early embryo development
viernes, diciembre 09, 2016
Author(s):
Xiaoqian Zhang,Xiaoqiu Liu,Mei Zhang,Tingting Li,Aaron Muth,Paul R Thompson,Scott A Coonrod,Xuesen Zhang
Source:
Scientific reports
Novel genetic loci underlying human intracranial volume identified through genome-wide association
martes, noviembre 08, 2016
Author(s):
Hieab H H Adams,Derrek P Hibar,Vincent Chouraki,Jason L Stein,Paul A Nyquist,Miguel E Rentería,Stella Trompet,Alejandro Arias-Vasquez,Sudha Seshadri,Sylvane Desrivières,Ashley H Beecham,Neda Jahanshad,Katharina Wittfeld,Sven J Van der Lee,Lucija Abramovic,Saud Alhusaini,Najaf Amin,Micael Andersson,Konstantinos Arfanakis,Benjamin S Aribisala,Nicola J Armstrong,Lavinia Athanasiu,Tomas Axelsson,Alexa Beiser,Manon Bernard,Joshua C Bis,Laura M E Blanken,Susan H Blanton,Marc M Bohlken,Marco P Boks,Janita Bralten,Adam M Brickman,Owen Carmichael,M Mallar Chakravarty,Ganesh Chauhan,Qiang Chen,Christopher R K Ching,Gabriel Cuellar-Partida,Anouk Den Braber,Nhat Trung Doan,Stefan Ehrlich,Irina Filippi,Tian Ge,Sudheer Giddaluru,Aaron L Goldman,Rebecca F Gottesman,Corina U Greven,Oliver Grimm,Michael E Griswold,Tulio Guadalupe,Johanna Hass,Unn K Haukvik,Saima Hilal,Edith Hofer,David Hoehn,Avram J Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Dalia Kasperaviciute,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil H Lee,Jiemin Liao,David C M Liewald,Lorna M Lopez,Michelle Luciano,Christine Macare,Andre Marquand,Mar Matarin,Karen A Mather,Manuel Mattheisen,Bernard Mazoyer,David R McKay,Rebekah McWhirter,Yuri Milaneschi,Nazanin Mirza-Schreiber,Ryan L Muetzel,Susana Muñoz Maniega,Kwangsik Nho,Allison C Nugent,Loes M Olde Loohuis,Jaap Oosterlaan,Martina Papmeyer,Irene Pappa,Lukas Pirpamer,Sara Pudas,Benno Pütz,Kumar B Rajan,Adaikalavan Ramasamy,Jennifer S Richards,Shannon L Risacher,Roberto Roiz-Santiañez,Nanda Rommelse,Emma J Rose,Natalie A Royle,Tatjana Rundek,Philipp G Sämann,Claudia L Satizabal,Lianne Schmaal,Andrew J Schork,Li Shen,Jean Shin,Elena Shumskaya,Albert V Smith,Emma Sprooten,Lachlan T Strike,Alexander Teumer,Russell Thomson,Diana Tordesillas-Gutierrez,Roberto Toro,Daniah Trabzuni,Dhananjay Vaidya,Jeroen Van der Grond,Dennis Van der Meer,Marjolein M J Van Donkelaar,Kristel R Van Eijk,Theo G M Van Erp,Daan Van Rooij,Esther Walton,Lars T Westlye,Christopher D Whelan,Beverly G Windham,Anderson M Winkler,Girma Woldehawariat,Christiane Wolf,Thomas Wolfers,Bing Xu,Lisa R Yanek,Jingyun Yang,Alex Zijdenbos,Marcel P Zwiers,Ingrid Agartz,Neelum T Aggarwal,Laura Almasy,David Ames,Philippe Amouyel,Ole A Andreassen,Sampath Arepalli,Amelia A Assareh,Sandra Barral,Mark E Bastin,Diane M Becker,James T Becker,David A Bennett,John Blangero,Hans van Bokhoven,Dorret I Boomsma,Henry Brodaty,Rachel M Brouwer,Han G Brunner,Randy L Buckner,Jan K Buitelaar,Kazima B Bulayeva,Wiepke Cahn,Vince D Calhoun,Dara M Cannon,Gianpiero L Cavalleri,Christopher Chen,Ching-Yu Cheng,Sven Cichon,Mark R Cookson,Aiden Corvin,Benedicto Crespo-Facorro,Joanne E Curran,Michael Czisch,Anders M Dale,Gareth E Davies,Eco J C De Geus,Philip L De Jager,Greig I de Zubicaray,Norman Delanty,Chantal Depondt,Anita L DeStefano,Allissa Dillman,Srdjan Djurovic,Gary Donohoe,Wayne C Drevets,Ravi Duggirala,Thomas D Dyer,Susanne Erk,Thomas Espeseth,Denis A Evans,Iryna O Fedko,Guillén Fernández,Luigi Ferrucci,Simon E Fisher,Debra A Fleischman,Ian Ford,Tatiana M Foroud,Peter T Fox,Clyde Francks,Masaki Fukunaga,J Raphael Gibbs,David C Glahn,Randy L Gollub,Harald H H Göring,Hans J Grabe,Robert C Green,Oliver Gruber,Vilmundur Gudnason,Sebastian Guelfi,Narelle K Hansell,John Hardy,Catharina A Hartman,Ryota Hashimoto,Katrin Hegenscheid,Andreas Heinz,Stephanie Le Hellard,Dena G Hernandez,Dirk J Heslenfeld,Beng-Choon Ho,Pieter J Hoekstra,Wolfgang Hoffmann,Albert Hofman,Florian Holsboer,Georg Homuth,Norbert Hosten,Jouke-Jan Hottenga,Hilleke E Hulshoff Pol,Masashi Ikeda,M Kamran Ikram,Clifford R Jack,Mark Jenkinson,Robert Johnson,Erik G Jönsson,J Wouter Jukema,René S Kahn,Ryota Kanai,Iwona Kloszewska,David S Knopman,Peter Kochunov,John B Kwok,Stephen M Lawrie,Hervé Lemaître,Xinmin Liu,Dan L Longo,W T Longstreth,Oscar L Lopez,Simon Lovestone,Oliver Martinez,Jean-Luc Martinot,Venkata S Mattay,Colm McDonald,Andrew M McIntosh,Katie L McMahon,Francis J McMahon,Patrizia Mecocci,Ingrid Melle,Andreas Meyer-Lindenberg,Sebastian Mohnke,Grant W Montgomery,Derek W Morris,Thomas H Mosley,Thomas W Mühleisen,Bertram Müller-Myhsok,Michael A Nalls,Matthias Nauck,Thomas E Nichols,Wiro J Niessen,Markus M Nöthen,Lars Nyberg,Kazutaka Ohi,Rene L Olvera,Roel A Ophoff,Massimo Pandolfo,Tomas Paus,Zdenka Pausova,Brenda W J H Penninx,G Bruce Pike,Steven G Potkin,Bruce M Psaty,Simone Reppermund,Marcella Rietschel,Joshua L Roffman,Nina Romanczuk-Seiferth,Jerome I Rotter,Mina Ryten,Ralph L Sacco,Perminder S Sachdev,Andrew J Saykin,Reinhold Schmidt,Peter R Schofield,Sigurdur Sigurdsson,Andy Simmons,Andrew Singleton,Sanjay M Sisodiya,Colin Smith,Jordan W Smoller,Hilkka Soininen,Velandai Srikanth,Vidar M Steen,David J Stott,Jessika E Sussmann,Anbupalam Thalamuthu,Henning Tiemeier,Arthur W Toga,Bryan J Traynor,Juan Troncoso,Jessica A Turner,Christophe Tzourio,Andre G Uitterlinden,Maria C Valdés Hernández,Marcel Van der Brug,Aad Van der Lugt,Nic J A Van der Wee,Cornelia M Van Duijn,Neeltje E M Van Haren,Dennis Van T Ent,Marie-Jose Van Tol,Badri N Vardarajan,Dick J Veltman,Meike W Vernooij,Henry Völzke,Henrik Walter,Joanna M Wardlaw,Thomas H Wassink,Michael E Weale,Daniel R Weinberger,Michael W Weiner,Wei Wen,Eric Westman,Tonya White,Tien Y Wong,Clinton B Wright,H Ronald Zielke,Alan B Zonderman,Ian J Deary,Charles DeCarli,Helena Schmidt,Nicholas G Martin,Anton J M De Craen,Margaret J Wright,Lenore J Launer,Gunter Schumann,Myriam Fornage,Barbara Franke,Stéphanie Debette,Sarah E Medland,M Arfan Ikram,Paul M Thompson
Source:
Nature neuroscience
A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22
miércoles, octubre 26, 2016
Author(s):
Hui-Hsin Chang,Guang-Yaw Liu,Nishant Dwivedi,Bo Sun,Yuko Okamoto,Jennifer D Kinslow,Kevin D Deane,M Kristen Demoruelle,Jill M Norris,Paul R Thompson,Jeffrey A Sparks,Deepak A Rao,Elizabeth W Karlson,Hui-Chih Hung,V Michael Holers,I-Cheng Ho
Source:
JCI insight
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
sábado, octubre 15, 2016
Author(s):
Tulio Guadalupe,Samuel R Mathias,Theo G M vanErp,Christopher D Whelan,Marcel P Zwiers,Yoshinari Abe,Lucija Abramovic,Ingrid Agartz,Ole A Andreassen,Alejandro Arias-Vásquez,Benjamin S Aribisala,Nicola J Armstrong,Volker Arolt,Eric Artiges,Rosa Ayesa-Arriola,Vatche G Baboyan,Tobias Banaschewski,Gareth Barker,Mark E Bastin,Bernhard T Baune,John Blangero,Arun L W Bokde,Premika S W Boedhoe,Anushree Bose,Silvia Brem,Henry Brodaty,Uli Bromberg,Samantha Brooks,Christian Büchel,Jan Buitelaar,Vince D Calhoun,Dara M Cannon,Anna Cattrell,Yuqi Cheng,Patricia J Conrod,Annette Conzelmann,Aiden Corvin,Benedicto Crespo-Facorro,Fabrice Crivello,Udo Dannlowski,Greig I de Zubicaray,Sonja M C de Zwarte,Ian J Deary,Sylvane Desrivières,Nhat Trung Doan,Gary Donohoe,Erlend S Dørum,Stefan Ehrlich,Thomas Espeseth,Guillén Fernández,Herta Flor,Jean-Paul Fouche,Vincent Frouin,Masaki Fukunaga,Jürgen Gallinat,Hugh Garavan,Michael Gill,Andrea Gonzalez Suarez,Penny Gowland,Hans J Grabe,Dominik Grotegerd,Oliver Gruber,Saskia Hagenaars,Ryota Hashimoto,Tobias U Hauser,Andreas Heinz,Derrek P Hibar,Pieter J Hoekstra,Martine Hoogman,Fleur M Howells,Hao Hu,Hilleke E Hulshoff Pol,Chaim Huyser,Bernd Ittermann,Neda Jahanshad,Erik G Jönsson,Sarah Jurk,Rene S Kahn,Sinead Kelly,Bernd Kraemer,Harald Kugel,Jun Soo Kwon,Herve Lemaitre,Klaus-Peter Lesch,Christine Lochner,Michelle Luciano,Andre F Marquand,Nicholas G Martin,Ignacio Martínez-Zalacaín,Jean-Luc Martinot,David Mataix-Cols,Karen Mather,Colm McDonald,Katie L McMahon,Sarah E Medland,José M Menchón,Derek W Morris,Omar Mothersill,Susana Munoz Maniega,Benson Mwangi,Takashi Nakamae,Tomohiro Nakao,Janardhanan C Narayanaswaamy,Frauke Nees,Jan E Nordvik,A Marten H Onnink,Nils Opel,Roel Ophoff,Marie-Laure Paillère Martinot,Dimitri Papadopoulos Orfanos,Paul Pauli,Tomáš Paus,Luise Poustka,Janardhan Yc Reddy,Miguel E Renteria,Roberto Roiz-Santiáñez,Annerine Roos,Natalie A Royle,Perminder Sachdev,Pascual Sánchez-Juan,Lianne Schmaal,Gunter Schumann,Elena Shumskaya,Michael N Smolka,Jair C Soares,Carles Soriano-Mas,Dan J Stein,Lachlan T Strike,Roberto Toro,Jessica A Turner,Nathalie Tzourio-Mazoyer,Anne Uhlmann,Maria Valdés Hernández,Odile A van den Heuvel,Dennis van der Meer,Neeltje E M van Haren,Dick J Veltman,Ganesan Venkatasubramanian,Nora C Vetter,Daniella Vuletic,Susanne Walitza,Henrik Walter,Esther Walton,Zhen Wang,Joanna Wardlaw,Wei Wen,Lars T Westlye,Robert Whelan,Katharina Wittfeld,Thomas Wolfers,Margaret J Wright,Jian Xu,Xiufeng Xu,Je-Yeon Yun,JingJing Zhao,Barbara Franke,Paul M Thompson,David C Glahn,Bernard Mazoyer,Simon E Fisher,Clyde Francks
Source:
Brain imaging and behavior
GnRH Stimulates Peptidylarginine Deiminase Catalyzed Histone Citrullination in Gonadotrope Cells
jueves, septiembre 08, 2016
Author(s):
Shaihla A Khan,Brian S Edwards,Aaron Muth,Paul R Thompson,Brian D Cherrington,Amy M Navratil
Source:
Molecular endocrinology (Baltimore, Md.)
Neutrophil extracellular traps exacerbate Th1-mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation
sábado, septiembre 03, 2016
Author(s):
Garyfalia Papadaki,Konstantinos Kambas,Christiana Choulaki,Katerina Vlachou,Elias Drakos,George Bertsias,Konstantinos Ritis,Dimitrios T Boumpas,Paul R Thompson,Panayotis Verginis,Prodromos Sidiropoulos
Source:
European journal of immunology
Tumor necrosis factor alpha, citrullination, and peptidylarginine deiminase 4 in lung and joint inflammation
lunes, julio 25, 2016
Author(s):
Mandar Bawadekar,Annette Gendron-Fitzpatrick,Ryan Rebernick,Daeun Shim,Thomas F Warner,Anthony P Nicholas,Lennart K A Lundblad,Paul R Thompson,Miriam A Shelef
Source:
Arthritis research & therapy
Nicotine induces neutrophil extracellular traps
sábado, junio 18, 2016
Author(s):
Ava Hosseinzadeh,Paul R Thompson,Brahm H Segal,Constantin F Urban
Source:
Journal of leukocyte biology
Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses
martes, mayo 24, 2016
Author(s):
Joanna Kawalkowska,Anne-Marie Quirke,Fatemeh Ghari,Simon Davis,Venkataraman Subramanian,Paul R Thompson,Richard O Williams,Roman Fischer,Nicholas B La Thangue,Patrick J Venables
Source:
Scientific reports
Peptidylarginine Deiminase 3 (PAD3) Is Upregulated by Prolactin Stimulation of CID-9 Cells and Expressed in the Lactating Mouse Mammary Gland
sábado, enero 23, 2016
Author(s):
Guangyuan Li,Isaac N Hayward,Brittany R Jenkins,Heather M Rothfuss,Coleman H Young,Marja T Nevalainen,Aaron Muth,Paul R Thompson,Amy M Navratil,Brian D Cherrington
Source:
PloS one
Protein Arginine Methylation and Citrullination in Epigenetic Regulation
martes, diciembre 22, 2015
Author(s):
Jakob Fuhrmann,Paul R Thompson
Source:
ACS chemical biology
Detection and identification of protein citrullination in complex biological systems
sábado, octubre 31, 2015
Author(s):
Kathleen W Clancy,Eranthie Weerapana,Paul R Thompson
Source:
Current opinion in chemical biology
Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer
miércoles, octubre 07, 2015
Author(s):
Erin E Witalison,Xiangli Cui,Corey P Causey,Paul R Thompson,Lorne J Hofseth
Source:
Oncotarget
Chemical Proteomic Platform To Identify Citrullinated Proteins
sábado, septiembre 12, 2015
Author(s):
Daniel M Lewallen,Kevin L Bicker,Venkataraman Subramanian,Kathleen W Clancy,Daniel J Slade,Julianne Martell,Christina J Dreyton,Jeremy Sokolove,Eranthie Weerapana,Paul R Thompson
Source:
ACS chemical biology
Utilization of the Soft Agar Colony Formation Assay to Identify Inhibitors of Tumorigenicity in Breast Cancer Cells
sábado, junio 13, 2015
Author(s):
Sachi Horibata,Tommy V Vo,Venkataraman Subramanian,Paul R Thompson,Scott A Coonrod
Source:
Journal of visualized experiments : JoVE
Inhibiting protein arginine deiminases has antioxidant consequences
sábado, enero 31, 2015
Author(s):
Erin E Witalison,Xiangli Cui,Anne B Hofseth,Venkataraman Subramanian,Corey P Causey,Paul R Thompson,Lorne J Hofseth
Source:
The Journal of pharmacology and experimental therapeutics
Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design
martes, enero 27, 2015
Author(s):
Daniel J Slade,Pengfei Fang,Christina J Dreyton,Ying Zhang,Jakob Fuhrmann,Don Rempel,Benjamin D Bax,Scott A Coonrod,Huw D Lewis,Min Guo,Michael L Gross,Paul R Thompson
Source:
ACS chemical biology
Common genetic variants influence human subcortical brain structures
jueves, enero 22, 2015
Author(s):
Derrek P Hibar,Jason L Stein,Miguel E Renteria,Alejandro Arias-Vasquez,Sylvane Desrivières,Neda Jahanshad,Roberto Toro,Katharina Wittfeld,Lucija Abramovic,Micael Andersson,Benjamin S Aribisala,Nicola J Armstrong,Manon Bernard,Marc M Bohlken,Marco P Boks,Janita Bralten,Andrew A Brown,M Mallar Chakravarty,Qiang Chen,Christopher R K Ching,Gabriel Cuellar-Partida,Anouk den Braber,Sudheer Giddaluru,Aaron L Goldman,Oliver Grimm,Tulio Guadalupe,Johanna Hass,Girma Woldehawariat,Avram J Holmes,Martine Hoogman,Deborah Janowitz,Tianye Jia,Sungeun Kim,Marieke Klein,Bernd Kraemer,Phil H Lee,Loes M Olde Loohuis,Michelle Luciano,Christine Macare,Karen A Mather,Manuel Mattheisen,Yuri Milaneschi,Kwangsik Nho,Martina Papmeyer,Adaikalavan Ramasamy,Shannon L Risacher,Roberto Roiz-Santiañez,Emma J Rose,Alireza Salami,Philipp G Sämann,Lianne Schmaal,Andrew J Schork,Jean Shin,Lachlan T Strike,Alexander Teumer,Marjolein M J van Donkelaar,Kristel R van Eijk,Raymond K Walters,Lars T Westlye,Christopher D Whelan,Anderson M Winkler,Marcel P Zwiers,Saud Alhusaini,Lavinia Athanasiu,Stefan Ehrlich,Marina M H Hakobjan,Cecilie B Hartberg,Unn K Haukvik,Angelien J G A M Heister,David Hoehn,Dalia Kasperaviciute,David C M Liewald,Lorna M Lopez,Remco R R Makkinje,Mar Matarin,Marlies A M Naber,D Reese McKay,Margaret Needham,Allison C Nugent,Benno Pütz,Natalie A Royle,Li Shen,Emma Sprooten,Daniah Trabzuni,Saskia S L van der Marel,Kimm J E van Hulzen,Esther Walton,Christiane Wolf,Laura Almasy,David Ames,Sampath Arepalli,Amelia A Assareh,Mark E Bastin,Henry Brodaty,Kazima B Bulayeva,Melanie A Carless,Sven Cichon,Aiden Corvin,Joanne E Curran,Michael Czisch,Greig I de Zubicaray,Allissa Dillman,Ravi Duggirala,Thomas D Dyer,Susanne Erk,Iryna O Fedko,Luigi Ferrucci,Tatiana M Foroud,Peter T Fox,Masaki Fukunaga,J Raphael Gibbs,Harald H H Göring,Robert C Green,Sebastian Guelfi,Narelle K Hansell,Catharina A Hartman,Katrin Hegenscheid,Andreas Heinz,Dena G Hernandez,Dirk J Heslenfeld,Pieter J Hoekstra,Florian Holsboer,Georg Homuth,Jouke-Jan Hottenga,Masashi Ikeda,Clifford R Jack,Mark Jenkinson,Robert Johnson,Ryota Kanai,Maria Keil,Jack W Kent,Peter Kochunov,John B Kwok,Stephen M Lawrie,Xinmin Liu,Dan L Longo,Katie L McMahon,Eva Meisenzahl,Ingrid Melle,Sebastian Mohnke,Grant W Montgomery,Jeanette C Mostert,Thomas W Mühleisen,Michael A Nalls,Thomas E Nichols,Lars G Nilsson,Markus M Nöthen,Kazutaka Ohi,Rene L Olvera,Rocio Perez-Iglesias,G Bruce Pike,Steven G Potkin,Ivar Reinvang,Simone Reppermund,Marcella Rietschel,Nina Romanczuk-Seiferth,Glenn D Rosen,Dan Rujescu,Knut Schnell,Peter R Schofield,Colin Smith,Vidar M Steen,Jessika E Sussmann,Anbupalam Thalamuthu,Arthur W Toga,Bryan J Traynor,Juan Troncoso,Jessica A Turner,Maria C Valdés Hernández,Dennis van 't Ent,Marcel van der Brug,Nic J A van der Wee,Marie-Jose van Tol,Dick J Veltman,Thomas H Wassink,Eric Westman,Ronald H Zielke,Alan B Zonderman,David G Ashbrook,Reinmar Hager,Lu Lu,Francis J McMahon,Derek W Morris,Robert W Williams,Han G Brunner,Randy L Buckner,Jan K Buitelaar,Wiepke Cahn,Vince D Calhoun,Gianpiero L Cavalleri,Benedicto Crespo-Facorro,Anders M Dale,Gareth E Davies,Norman Delanty,Chantal Depondt,Srdjan Djurovic,Wayne C Drevets,Thomas Espeseth,Randy L Gollub,Beng-Choon Ho,Wolfgang Hoffmann,Norbert Hosten,René S Kahn,Stephanie Le Hellard,Andreas Meyer-Lindenberg,Bertram Müller-Myhsok,Matthias Nauck,Lars Nyberg,Massimo Pandolfo,Brenda W J H Penninx,Joshua L Roffman,Sanjay M Sisodiya,Jordan W Smoller,Hans van Bokhoven,Neeltje E M van Haren,Henry Völzke,Henrik Walter,Michael W Weiner,Wei Wen,Tonya White,Ingrid Agartz,Ole A Andreassen,John Blangero,Dorret I Boomsma,Rachel M Brouwer,Dara M Cannon,Mark R Cookson,Eco J C de Geus,Ian J Deary,Gary Donohoe,Guillén Fernández,Simon E Fisher,Clyde Francks,David C Glahn,Hans J Grabe,Oliver Gruber,John Hardy,Ryota Hashimoto,Hilleke E Hulshoff Pol,Erik G Jönsson,Iwona Kloszewska,Simon Lovestone,Venkata S Mattay,Patrizia Mecocci,Colm McDonald,Andrew M McIntosh,Roel A Ophoff,Tomas Paus,Zdenka Pausova,Mina Ryten,Perminder S Sachdev,Andrew J Saykin,Andy Simmons,Andrew Singleton,Hilkka Soininen,Joanna M Wardlaw,Michael E Weale,Daniel R Weinberger,Hieab H H Adams,Lenore J Launer,Stephan Seiler,Reinhold Schmidt,Ganesh Chauhan,Claudia L Satizabal,James T Becker,Lisa Yanek,Sven J van der Lee,Maritza Ebling,Bruce Fischl,W T Longstreth,Douglas Greve,Helena Schmidt,Paul Nyquist,Louis N Vinke,Cornelia M van Duijn,Luting Xue,Bernard Mazoyer,Joshua C Bis,Vilmundur Gudnason,Sudha Seshadri,M Arfan Ikram,Alzheimer’s Disease Neuroimaging Initiative,CHARGE Consortium,EPIGEN,IMAGEN,SYS,Nicholas G Martin,Margaret J Wright,Gunter Schumann,Barbara Franke,Paul M Thompson,Sarah E Medland
Source:
Nature
Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors
miércoles, enero 07, 2015
Author(s):
Venkataraman Subramanian,Jason S Knight,Sangram Parelkar,Lynne Anguish,Scott A Coonrod,Mariana J Kaplan,Paul R Thompson
Source:
Journal of medicinal chemistry
Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion
martes, diciembre 09, 2014
Author(s):
Min Wang,Jakob Fuhrmann,Paul R Thompson
Source:
Biochemistry
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