Protein synthesis (translation) lies at the heart of gene expression regulation during organism development, cellular homeostasis and disease. We use structural biology - including X-ray crystallography and electron cryo-microscopy (cryo-EM) - and biochemistry to understand molecular mechanisms of translation regulation on bacterial and eukaryotic ribosomes. The studies are designed to expand fundamental understanding of central cellular processes and to pave the way for the development of therapeutics that would target translation regulation.
Rotation Positions for PhD and MD/PhD students are available.
